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Tree Shrews, Our New Best Friend in Human Diseases Study?
In the long history of biomedical research, animals are always the non-replaceable parts. During the last four decades, 99% of the laureates of Noble Prize in Physiology and Medicine won the honor referring to their animal-based research. For human diseases study specifically, although the non-human primates, such as rhesus monkey, do have their undeniable advantages, the disadvantages are also... more
Coat Color of Kunming Dog populations is under Balancing Selection
No matter how small it is, almost every aspect of biology’s life is under the close watch of evolutionary selection. And the influence of selection could show in different ways. For example, directional selection is a mode in which the best man wins, which means a single phenotype will be favored and the allele frequency will continuously shift in one direction. But one the other hand, there a... more
The Evolution of Tree Frogs Helps Pinpoint the Time of Collision Between Indian and Asia
When the Indian subcontinent collided with the Eurasian plate, many animals and plants from Africa and Madagascar dispersed into Asia. The event triggered the biotic diversification of many species — one species of particular interest is the rhacophorid tree frog.
Early studies have suggested that the India–Asia collision occurred during the Paleocene or Early Eocene, around 66–56 million ye... more
A Gut Feeling: New insights into Bacterial Microbiomes association with Colorectal Cancer among Han Chinese
Despite the prevalence of colorectal cancer (CRC) around the world in general and China in particular, relatively little is known about the underlying causal mechanisms of CRC. Current research that has attempted to find novel risk factors for these disorders suggests that alongside the traditional risks of dietary, genetic, and environmental factors, bacterial infections may play a significant... more
First Goat Genome Sets a Good Example for Facilitating De Novo Assembly of Large Genomes

Goats. (Credit: © Dimitar Marinov / Fotolia)
Dec. 23, 2012 — In a collaborative study published online today in Nature Biotechnology, researchers from Kunming Institute of Zoology, Chinese Academy of Sciences, BGI, and other institutes, have completed the first genome sequence of domestic goat by a robust approach integrated with next-generation sequencing (NGS) and whole-genome mapping (WGM... more
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