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RETSAT mutation selected for hypoxia adaptation inhibits tumor growth

  High altitude is one of the most extreme environments worldwide, and mammals living in high altitude evolve adaptation traits including respiratory, cardiovascular, and metabolic systems compared to reciprocal lowlanders.
  The genetic signals after hypoxia positive selection are the major factors contributing to the hypoxia tolerant physiological traits, some of which have been indicate... more
Researchers Uncover a Strategy for Efficient preparation of genus-specific diagnostic antibodies for snakebites

  There are at least 768 species of venomous snakes in the world. As said by former United Nations secretary general Kofi Annan, ‘Snakebite is the most important tropical disease you’ve never heard of’. The number of people bitten by snakes in the world is 1.8-2.7 million every year, causing more than 125,000 deaths. In China, 200,000-400,000 people are bitten by snakes every year, result... more
Researchers reveal the molecular regulatory mechanism in schizophrenia susceptibility locus 2q33.1

  A research team led by Prof. LUO Xiongjian from Kunming Institute of Zoology of the Chinese Academy of Sciences reported the regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression. The finding was published in Brain on 28th September, 2021.
  Schizophrenia, the heritability around 79-81%, is a severe and chronic psychiatric disorder with about 1... more
New version of Chinese tree shrew genome annotation was released

  A research team led by Prof. YAO Yonggang from Kunming Institute of Zoology of the Chinese Academy of Sciences, has reported a new version of Chinese tree shrew genome annotation and studied multiple genomic and transcriptomic characteristics of Chinese tree shrew, including gene family expansion, transcriptomic similarity across four species, and host immune response against virus infecti... more
The Researchers Discover New Echolocating Mammalian Lineage
In a study published in Science, a research group led by Prof. SHI Peng from Kunming Institute of Zoology of the Chinese Academy of Sciences reported a new echolocating mammalian lineage in rodents, illustrating the underestimated bio-diversity of adaptive complex traits, and offering a potential animal model to investigate the behavioral, physiological, and molecular mechanisms of echolocation... more
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