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How and Why Men and Women Differ in Their Microbiomes?

  In a paper published very recently in Advanced Science, Prof. Sam MA and Ms. Wendy LI from Kunming Institute of Zoology, Chinese Academy of Sciences present seven aspects of the sex differences in the human microbiomes at 15 body sites, including oral, gut, skin and airway.
  Formally, the sex differences or sexual dimorphism in the human microbiomes are referred to as microgenderome, a ... more
Integrative Analysis Identified BTN3A2 as a Novel Schizophrenia Risk Gene

  Schizophrenia is a complex, highly heritable and heterogeneous disease with estimated heritability ranging up to 80%. It affects approximately 0.5-1% of the world population and causes significant global burdens. During the past decade, the genome-wide association studies (GWASs) have identified numerous schizophrenia-associated variants and loci in world-wide populations, but most of the ... more
Tumor Genome as “Living Fossil” Reveals Ancient Introgression from Coyotes to Pre-contact Dogs in North America

  Canine transmissible venereal tumor (CTVT), the oldest known somatic cell line, is a “living fossil” of the original host, transmitted from its tumor cells to other canids during the mating process. Since it was shown ten years ago that living cells from an ancient host could be transmitted among canids, the origin of CTVT has been studied continuously.
  Recent comparison of the CTVT ... more
Researchers Decipher Forces Shaping Maternal Genetic Landscape of Han Chinese

  As the world’s largest ethnic group, the genetic landscape of Han Chinese had been widely concerned during the last decades. Previous studies based on mitochondrial DNA (mtDNA) variants indicated a north-south maternal genetic divergence among Han populations. However, these studies mainly based on low-resolution mtDNA data of relatively limited samples, making the maternal genetic landsc... more
Scientists Lead to Reveal the Molecular Basis for Heat Desensitization of TRPV1 Ion Channels
 TRPV1 is an important temperature sensing element in mammals, which can be activated by high temperatures above 40°C. However, its role in sustained heat response remains poorly understood since a rapid heat-induced desensitization (Dh) process follows a tightly heat-induced activation (Ah) phase, and its function in mammalian biological activities remain elusive.
  Recently, scientists fro... more
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