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Researchers Found New Evidences for Developing KLF5 as a Biomarker and Therapeutic Target for Breast Cancer Treatment

  Breast cancer is one of the most common malignancies in women, recent researches indicated that transcription factor Krüpple-like factor 5 (KLF5) plays important roles in breast tumorigenesis. The previous studies showed KLF5 promotes breast cancer stem cell maintenance and self-renewal (Theranostics, 2016; 6(4): 533-544), it is also reported that Klf5 plays a key role in maintaining ESC ... more
Scientists Revealed a Novel Role of Signal Peptide for Glutamate Receptor Trafficking

  In our brain, there are around 10 billion neurons and the neural synapses are the basic and connection units transferring the information between them. The neural transmitters, released by presynaptic neurons, diffuse into the synaptic cleft and then bind to the corresponding receptors on postsynaptic neurons, thereby regulating their neuronal activity and accomplishing the information tra... more
A new cyprinid fish was discovered from Irrawaddy River in Northern Myanmar

  Puta-O region, located in the Northernmost part of Myanmar, is one of the world's highest biodiversity hotspots and the species richness is extremely high. Since December 2014, researchers from Kunming Institute of Zoology (KIZ)/Southeast Asia Biodiversity Research Institute (SEARBI), Chinese Academy of Sciences have collected some fish specimens during the surveys of the Mali Hka River dr... more
Researchers decipher the dynamic evolutionary patterns of high-elevation adaptation

  Adaptation to extreme environmental conditions is one of the major topics of evolutionary biology. High elevations provide extreme environments challenging the survival of many species. It is of strategic and scientific significance to study the mechanism of Plateau adaptation, especially given that China has the largest plateau areas in the world.
  In particular, the Qinghai-Tibetan Pl... more
Four new species of Triplophysa were found in China

  Triplophysa is an ecologically important and taxonomically challenging genus distributed in lakes, rivers, and streams of the Qinghai-Tibetan Plateau and adjacent regions. Species of Triplophysa are distributed westward to the Aral Sea basin and across interior drainages of Baluchistan and northwestward to Western Mongolia and adjoining Russia. Recently, scientists found four new member of... more
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