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Researchers Illustrate Multiple Functional Variations Correlated with the Heritable Risk of Schizophrenia

  Complex psychiatric illnesses, such as schizophrenia, are bringing significant threat to public well-being, yet clinical diagnosis and management of these illnesses remain less successful due to a lack of knowledge of their pathogenesis. Recent genome-wide association studies (GWAS) have identified numerous non-coding variations significantly associated with schizophrenia, but the potentia... more
Researchers found the tropical Bos gaurus and Dicerorhinus sumatrensis inhabit in Tibet Plateau ~5,200 years ago

  A research team led by Prof. SU Bing from Kunming Institute of Zoology of the Chinese Academy of Sciences, collaborating with the researchers from Lanzhou University and Northwest Agriculture and Forestry University, performed aDNA investigation on approximately 5,200-years-old bovid and rhinoceros specimens from the Shannashuzha (SNSZ) site, and revealed that the tropical Bos gaurus and D... more
Researchers Reveal Secretory Cell Endolysosome Channel Mediated Antigen Presentation

  The immune system plays vital roles in protecting host against a wide variety of pathogenic organisms and malignant cells. Acquired immunity is a specific immune protection system with immunological memory to recognize specific antigen. Antigen presentation is the first step of acquired immunity which mediated by professional antigen-presenting cells for antigen uptake, processing and pres... more
Researchers reveal the molecular mechanism of stroke induced by iron deficiency anemia and the use oral contraceptives

  Ischemic stroke is usually caused by vascular obstruction, accounting for about 87% of stroke. In short, ischemic stroke occurs after severe reduction or interruption of cerebral blood flow caused by vascular occlusion. At present, ischemic stroke is the second leading cause of death in the world and the most important cause of permanent disability. Both factors, including iron deficiency ... more
Target switch of centipede toxins for antagonistic switch

  Animal venoms are powerful, highly evolved chemical weapons for defense and predation. While venoms are used mainly to lethally antagonize heterospecifics (individuals of a different species), nonlethal envenomation of conspecifics (individuals of the same species) is occasionally observed. Both the venom and target specifications underlying these two forms of envenomation are still poorly... more
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