Scientists

吴东东
Dong-Dong Wu / Deputy Director of the Kunming Institute of Zoology, Chinese Academy of Sciences
Lab/Research Group Name:Primate Evolution, Geneticsand Development Laboratory
Email:wudongdong@mail.kiz.ac.cn
Phone:+86 871 68526518
Zip Code:650201
Address:No.17 LongXin Road, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
Position:Professor, Principal Investigator, Research Professor. Director, Deputy Director of the Kunming Institute of Zoology,Director of the of the State Key Laboratory of Genetic Evolution & Animal Models.
Lab/Personal Website:http://wulab.kiz.ac.cn/

Education and Appointments

Education

Degree Field Institution Year

Ph.D. Fudan University 2002/092006/07

B.S./B.A. Kunming Institute of Zoology, Chinese Academy of Sciences 2006/09—2011/01


Professional Experience

Position Institution Years Include faculty appointments, postdoctoral positions, visiting professorships, etc.

Kunming Institute of Zoology, Chinese Academy of Sciences 2011/012016/01 Associate Researcher

Kunming Institute of Zoology, Chinese Academy of Sciences Since 2016/01 Researcher, Doctoral Supervisor

Kunming Institute of Zoology, Chinese Academy of Sciences Since 2025/02 Deputy Director


Research Areas

Taking non-human primates as the research subjects, interdisciplinary approaches are employed to investigate the origins and evolutionary mechanisms underlying the complex traits of primates, thereby advancing the application of non-human primates in biomedicine. As the initiator, he led and launched the International Primate Genome Project.

Supported Projects

National Key Research and Development Program of China

Analysis of Brain Disease Model Pathomics Atlas and Database Creation

Project leader

2021YFF0702703

2021-12-1 to 2024-11-30

RMB 750,000


Chinese Academy of Sciences "Western Light-Western Cross-Team" Key Laboratory Special Project

Evolution of Primate Diversity

Project leader

2023-1-1 to 2025-12-31

RMB 2,000,000


Yunnan Xingdian Talent Support Program - Yunling Scholar

Genetic Mechanisms of Rapid Evolution in the Primate Brain

Project leader

2025-1-1 to 2027-12-31

RMB 7,300,000


National Natural Science Foundation of China Youth Science Fund Project (Category A)

Primate Evolutionary Genetics

Project leader

2026-1-1 to 2030-12-31

RMB 4,000,000


Yunnan Provincial Department of Science and Technology Major Science and Technology Special Project Plan

International Primate Genome Project – Research on the Analysis of Complex Traits and Construction of Disease Models in Non-Human Primates

Project leader

2025-12-1 to 2030-11-30

RMB 15,000,000


Awards and Honors

Award/Honor

Awarding

Organization Year

Genomic Diversity and Evolution of Asian Populations

The State Council of the People's Republic of China

2014.12.12

Genomic Diversity and Evolution of Asian Populations

The People's Government of Yunnan Province

2014.4.1

Molecular Mechanisms of Animal Adaptive Evolution

The People's Government of Yunnan Province

2014.4.1

Origin and Domestication of Domestic Animals

The People's Government of Yunnan Province

2021.6.2

Outstanding Member of the CAS Youth Innovation Promotion Association (YIPA)

Chinese Academy of Sciences (CAS)

2017.11.3

Changlong Award of the Chinese Society of Zoology

Chinese Society of Zoology

2022.12.27

Yunling Most Beautiful Science and Technology Worker

Yunnan Provincial Department of Science and Technology, Propaganda Department of the Yunnan Provincial Committee of the CPC, Yunnan Association for Science and Technology, Kunming Branch of Chinese Academy of Sciences

2023.7.1

Unraveling the Mysteries of Primate Evolution

Science and Technology Review Press

2024.1.6

CAS May Fourth Youth Medal

Chinese Academy of Sciences (CAS)

2024.5

18th China Youth Science and Technology Award

China Association for Science and Technology (CAST)

2024.11.17

Yunnan Provincial Youth Science and Technology Award

Yunnan Association for Science and Technology

2024.11.13

CAS Youth Scientist Award

Chinese Academy of Sciences (CAS)

2025.1

Tengchong outstanding young scientists award

Tengchong Scientist Forum

2025.12


Publications

1. Wang S, Chen Z, Luo A, You X, Kitchener AC, Tu X, Thakur M, Umapathy G, Hu S, Zhang T, Zhang Y, Liu S, Ding Y, Liu F, Dai Q, Feng X, Li L, Pan Y, Zhang M, Roos C, Fan P#, Fu Q#, Wu DD#. Genome sequences of extant and extinct gibbons reveal their phylogeny, demographic history, and conservation status. Cell. 2025 S0092-8674(25)01181-X.

2. Shao Y, Zhou L, Li F, Zhao L, Zhang BL, Shao F, Chen JW, Chen CY, Bi XP, Zhuang XL, Hu J, Sun Z, Li X, Wang D, Wang S, Wang YM, Chen W, Li G, Lu HM, Liu Y, Fan PF, Yu L, Li M, Liu ZJ, Tiley GP, Yoder AD, Roos C, Hayakawa T, Marques-Bonet T, Rogers J, Yao YG, Zhang YP, Wang W, Qi XG#, Zhang G#, Wu DD#. Phylogenomic analyses provide insights into primate evolution. Science. 2023 380(6648):913-924.(封面论文)

3. Qi XG #, Wu J, Zhao L, Wang L, Guang X, Garber PA, Opie C, Yuan Y, Diao R, Li G, Wang K, Pan R, Ji W, Sun H, Huang Z, Xu C, Witarto AB, Jia R, Zhang C, Deng C, Qiu Q, Zhang G, Grueter C#, Wu DD#, Li B #. Adaptations to a cold climate promoted social evolution in Asian colobine primates. Science. 2023 380(6648):eabl8621

4. Zhang BL, Chen Y, Zhang Y, Qiao Y, Wu Y, Zhang Y, Lu Y, You X, Li Y, Huang HD, Wang Q, Li Y, Wang Y, Xiao W, Duan H, Qiu MH, Chen NH, Yu X, Yang MM, Lv L, Cooper DN, Zheng P, Yao YG#, Liu N#, Wang JH#, Wu DD#. Forward and reverse genomic screens enhance the understanding of phenotypic variation in a large Chinese rhesus macaque cohort. Nature Communications. 2025 16(1):8703.

5. Zhang BL, Chen W, Wang Z, Pang W, Luo MT, Wang S, Shao Y, He WQ, Deng Y, Zhou L, Chen J, Yang M, Wu Y, Wang L, Fernandez H, Molloy S, Meunier H, Wanert F, Kuderna L, Marques-Bonet T, Roos C, Qi X, Li M, Liu ZJ, Schierup MH, Cooper DN, Liu J, Zheng YT#, Zhang G#, Wu DD #. Comparative genomics reveal hybrid speciation of a macaque group. Science Advances. 2023 9(22):eadd3580.

6. Bi X, Zhou L, Zhang J, Feng S, Hu M, Cooper DN, Lin J, Li J, Wu DD#, Zhang GJ#. Lineage-specific accelerated sequences underlying primate evolution. Science Advances. 2023 9(22):eadc9507

7. Li ML, Wang S, Xu P, Tian HY, Bai M, Zhang YP, Shao Y, Xiong ZJ, Qi XG, Cooper DN, Zhang G, Zhu HH, Wu DD#. Functional genomics analysis reveals the evolutionary adaptation and demographic history of slow lorises. PNAS. 2022 119(40):e2123030119. (封面论文)

8. Ayoola AO, Zhang BL#, Meisel RP, Nneji LM, Shao Y, Morenikeji OB, Adeola AC, Ng'ang'a SI, Ogunjemite BG, Okeyoyin AO, Roos C, Wu DD#. Population Genomics Reveals Incipient Speciation, Introgression, and Adaptation in the African Mona Monkey (Cercopithecus mona). Molecular Biology and Evolution 2021 38(3):876-890.

Member

Research Team

Staff

Dr. Lin Zeng, Associate Research Fellow

Dr. Baolin Zhang, Associate Research Fellow

Dr. Sheng Wang, Associate Research Fellow

Dr. Hangyu Tian, Assistant Research Fellow

Dr. Xiaolin Zhuang, Assistant Research Fellow

Dr. Jinjin Zhang, Assistant Research Fellow

M.M. Yang, Master, Experimentalist


Graduate Students

Xiaolong Tu, Ph.D. Candidate (Enrolled 2021)

Ningyawen Liu, Ph.D. Candidate (Enrolled 2021)

Yongxuan Chen, Ph.D. Candidate (Enrolled 2022)

Yizheng Lu, Ph.D. Candidate (Enrolled 2023)

Ayun Luo, Ph.D. Candidate (Enrolled 2024)

Boyang Wu, Master’s Candidate (Enrolled 2023)

Yu Zhang, Master’s Candidate (Enrolled 2025)