（1）Educational Experience

Sep. 1996 to July 2000, Southwest University, College of Life Sciences, Bachelor Degree.

Sep. 2000 to July 2003, Southwest University, College of Life Science, Master Degree.

Sep. 2003 to Mar. 2007, The Chinese University of Hong Kong, College of Environment Science, Doctor Degree.

Oct. 2008 to Apr. 2013, University of Massachusetts Medical School, Department of Molecular, Cell and Cancer Biology, Post-doctor.

（2） Research and Academic Work Experience

May 2007 to Oct. 2008, The Chinese University of Hong Kong, College of Traditional Chinese Medicine, Research Assistant

Apr. 2013 to Now, Kunming Institute of Zoology, Chinese Academy of Sciences, Principal Investigator

Research Group Positioning

Development and tumorigenesis of mammary gland

(1) Regulatory mechanism of mammary gland stem cells and breast cancer stem cells;

(2) Mammary gland development across various wildlives

(3) Screening and identification of natural compounds from Yunnan herbal extracts for inhibition of breast cancer progression.

The third prize of Yunnan Province Natural Science Award，

1.     Shao H#, Huang J#, Wang H#, Wang G#, Yang X, Cheng M, Sun C, Zou L, Yang Q, Zhang D, Liu Z, Jiang X, Shi L, Shi P, Han B*, Jiao B*. Fused in sarcoma (FUS) inhibits milk production efficiency in mammals. Nature Communications. 2024 May 10;15(1):3953.

2.     Yang X#, Xu H#, Yang X, Wang H, Zou L, Yang Q, Qi X, Li L, Duan H, Yan X, Fu NY, Tan J*, Hou Z*, Jiao B*. Mcam inhibits macrophage-mediated development of mammary gland through non-canonical Wnt signaling. Nature Communications. 2024 Jan 2; 15(1):36.

3.     Wang H, Xu H，Chen W, Cheng M, Zou L, Yang Q, Chan C B, Zhu H, Chen C, Nie J, Jiao B*. Rab13 sustains breast cancer stem cells by supporting tumor- stroma crosstalk, Cancer Research, 2022. Jun 6; 82(11):2124-2140.

4.     Zhao L#, Qiu T#, Jiang D#, Xu H, Zou L, Yang Q, Chen C*, Jiao B*. 2020. SGCE promotes breast cancer stem cells by stabilizing EGFR. Advanced Science. 2020. June 08. 7(14):1903700.

5.     Zhao L#, Ke H#, Xu H, Wang G, Zhang H, Zou L, Xiang S, Li M, Peng L, Zhou M, Li L, Ao L, Yang Q, Shen C J, Yi P*, Wang L*, Jiao B*. 2020. TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Xdh and Btn1a1. Nature Communications. 2020. Jan 17;11(1):341.

6.     Ke H#, Zhao L#, Zhang H#, Feng X, Xu H, Hao J, Wang S, Yang Q, Zou L, Su X, Wang L, Wu C, Wang Y, Nie J, Jiao B*, 2018. Loss of TDP43 inhibits progression of triple-negative breast cancer in coordination with SRSF3. Proc Natl Acad Sci U S A. 115(15):E3426-E3435.

7.     Jiao B, Ma H, Shokhirev M, Drung A, Yang Q, Shin J, Lu S, Byron M, Kalantry S, Mercurio AM, Lawrence JB, Hoffmann A. and Bach I. 2012. Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. Cell. 149:630-41.

National Key Research Project, Evolutionary Developmental Mechanisms of Mammalian Mammary Gland and Cerebral Neocortex, 2023YFA1800500, 2023.12-2028.11