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Principal Investigator
Details of the Faculty or Staff
Name  
Jiang-Wei Lin
Title  
  Professor
Highest Education 
  Ph.D
Address  
Kunming Institute of Zoology, the Chinese Academy of Sciences, 17 longxin road, Kunming, Yunnan, 650223, China
Phone  
  
Zip Code  
  650203
Fax  
  
E-mail  
  linjiangwei@mail.kiz.ac.cn

Education and Appointments:

Jiang-Wei Lin, Ph.D., Professor & Principal Investigator

E-mail: linjiangwei@mail.kiz.ac.cn

 

2019.9-Present: Principal Investigator, Kunming Institute of Zoology, Chinese Academy of Sciences

2018.4-2019.9: Postdoctoral Fellow, Helmholtz Zentrum München, Institute of Epigenetics and Stem Cells

2012.9-2018.4: Ph.D., Max Planck Research Unit for Neurogenetics

2009.7-2012.7: Research assistant, Shanghai Institute of Biochemistry and Cell Biology, SIBS, CAS

2006.9-2009.6: M.Sc., Yangzhou University

2001.9-2005.6: B.Sc., Hunan Normal University


Research Interests:

The major interests of our lab are somatic cell nuclear transfer in non-human primates, embryonic derived stem cell lines and gene editing.

Public Services:

Honors:
 
Selected Publication:

1. Nakatani,T., Lin, J., Ji, F., Ettinger, A., Pontabry, J., Tokoro, M., Altamirano-Pacheco, L., Fiorentino,J., Mahammadov, E., Hatano, Y., Van Rechem, C., Chakraborty, D., Ruiz-Morales, E., Arguello Pascualli, P., Scialdone, A., Yamagata, K., Whetstine, J.R., Sadreyev, R., Torres-Padilla,M. (2022). DNA replication fork speed underlies cell fate changes and promotes reprogramming. Nature Genetics .54,318-327

 

2. Lin, J. (2022). SOX17 Is not required for the derivation and maintenance of mouse extraembryonic endoderm stem cell lines. bioRxiv preprint doi: https://doi.org/10.1101/2022.01.09.475525.

 

3. Lin, J. (2021). The origin of mouse extraembryonic endoderm stem cell lines. bioRxiv preprint doi: https://doi.org/10.1101/2021.12.27.474300.

 

4. Lin, J., Khan, M., Zapiec, B., Mombaerts, P. (2017). PDGFRA is not essential for the derivation and maintenance of mouse extraembryonic endoderm stem cell lines. Stem Cell Reports 9, 1062–1070.

 

5.Lin, J., Khan, M., Zapiec, B., Mombaerts, P. (2016). Efficient derivation of extra-embryonic endoderm stem cell lines from mouse post-implantation embryos. Scientific Reports 6, 39457; doi: 10.1038/srep39457.

 

6. Katidou, M., Grosmaitre, X., Lin, J., Mombaerts, P. (2018). G-protein coupled receptors Mc4r and Drd1a can serve as surrogate odorant receptors in mouse olfactory sensory neurons. Molecular and Cellular Neuroscience 88, 138147.

 

7. Koentgen, F., Lin, J., Katidou, M., Chang, I., Khan, M., Watts, J., Mombaerts, P. (2016). Exclusive transmission of embryonic stem cell-derived genome through the mouse germline. Genesis 54, 326–333. 

 

8. Qin, Y., Lin, J., Zhou, C., Yin, Q., Xie, Z., Zhang, X., Liu, X.Y., Gao, W., Li, J. (2013). Mice cloned from white adipose tissue-derived cells. J. Mol. Cell. Biol. 5, 348-350.

 

9. Lin, J., Shi, L., Zhang, M., Yang, H., Qin, Y., Zhang, J., Gong, D., Zhang, X., Li, D., Li, J. (2011). Defects in trophoblast cell lineage account for the impaired in vivo development of cloned embryos generated by somatic nuclear transfer. Cell Stem Cell 8, 371–375.

 

10.Jiang, J., Ding, G., Lin, J., Zhang, M., Shi, L., Lv, W., Yang, H., Xiao, H., Pei, G., Li, Y., Wu, J., Li, J. (2011). Different developmental potential of pluripotent stem cells generated by different reprogramming strategies. J. Mol. Cell. Biol 3,197-199.

 

11. Li, X., Zhu, L, Yang, A., Lin, J., Tang, F., Jin, S., Wei, Z., Li, J., Jin, Y. (2011). Calcineurin-NFAT signaling critically regulates early lineage specification in mouse embryonic stem cells and embryos. Cell Stem Cell 8, 46-58.

 

12. Yang, H., Shi, L., Zhang, S., Lin, J., Jiang, J., Li, J. (2010). High-efficiency somatic reprogramming induced by intact MII oocytes. Cell Res. 20,1034-1042


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