Journal Article:
[1] Huang YQ#, Ge MX#, Li YH#, Li JL, Yu Q, Xiao FH, Ao HS, Yang LQ, Li J*, He YH*, Kong QP*. 2022. Longevity-associated transcription factor ATF7 promotes healthspan by suppressing cellular senescence and systematic inflammation. Aging and disease, 1-16.
[2] Ge MX, Hu L, Ao HS, Zi MT, Kong QP*, He YH*. 2021. Senolytic targets and new strategies for clearing senescent cells. Mechanisms of Ageing and Development, 195, 111468.
[3] He YH#, Zhang X(uan)#, Chang JH#, Kim H#, Zhang PY, Wang YY, Khan S, Liu XG, Zhang X(in), Lv DW, Li W, Thummuri D, Yuan YX, Elisseeff J, Campisi J, Almeida M, Song L, Zheng GR*, Zhou DH*. 2020. Using Proteolysis-Targeting Chimera Technology to Reduce Navitoclax Platelet Toxicity and Improve Its Senolytic Activity. Nature Communications, 11(1), 1996.
[4] He YH, Koch R, Budamagunta V, Zhang PY, Zhang X(uan), Khan S, Thummuri D, Ortiz Y. T, Zhang X(in), Lv DW, Wiegand J. S, Li W, Palmer A. C, Zheng GR, Weinstock D. M*, Zhou DH*. 2020. DT2216–a Bcl-xL specific degrader is highly active against Bcl-xL-dependent T-cell lymphomas. Journal of Hematology & Oncolog, 13(1), 95.
[5] He YH, Wen Li, Lv DW, Zhang Xin, Zhang X, Campisi Judith, Zheng GR, Zhou DH*. 2020. Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity. Aging Cell, 19(3), 13117.
[6] He YH#, Khan S#, Huo ZG, Lv DW, Zhang X, Liu XG, Yuan YX, Hromas R, Xu MJ, Zheng GR, Zhou DH. 2020. Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies. Journal of Hematology & Oncology, 13(1), 103.
[7] Khan S#, He YH#, Zhang X, Yuan YX, Pu SY, Kong QP, Zheng GR, Zhou DH*. 2020. PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics. Oncogene, 39(26), 4909-4924.
[8] Zhang X#, He YH#, Zhang PY#, Budamagunta V, Lv DW, Thummuri D, Yang Y, Pei J, Yuan YX, Zhou DH*, Zheng GR*. 2020. Discovery of IAP-Recruiting BCL-XL PROTACs as Potent Degraders across Multiple Cancer Cell Lines. European Journal of Medicinal Chemistry, 199, 112397.
[9] Khan Sajid#, Zhang X#, Lv DW#, Zhang Q, He YH, Zhang PY, Yuan YX, Liu XG, Thummuri Dinesh, Wiegand Janet, Ferrando Adolfo, Hromas Robert, Konopleva Maria, Zheng GR*, Zhou DH*. 2019. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nature Medicine, 25(12), 1938-1947.
[10] He YH, Thummuri D, Zheng GR, Okunieff P, Citrin DE, Vujaskovic Z, Zhou DH*. 2019. Cellular Senescence and Radiation-induced Pulmonary Fibrosis. Translational Research, 209, 14-21.
[11] Li W#, Qin L#, Feng RN, Hu GR, Sun H, He YH*, RP Zhang*. 2019. Emerging senolytic agents derived from natural products. Mechanisms of Ageing and Development, 181, 1-6.
[12] Xiao FH#, Chen XQ#, Yu Q#, Ye YS#, Liu YW, Yan DJ, Yang LQ, Chen GJ, Lin R, Yang LP, Liao XP, Zhang W, Zhang W, Wang XF, Zhou JM*, Cai WW*, He YH*, Kong QP*. 2018. Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians. Genome Research, 28(11), 1601-1610.
[13] Li QG#, He YH#, Wu H#, Yang CP, Pu SY, Fan SQ, Jiang LP, Shen QS, Wang XX, Chen XQ, Yu Q, Li Y, Sun C, Wang XT, Zhou JM, Li HP, Chen YB*, Kong QP*. 2017. A normalization-free and nonparametric method sharpens pan-cancer expression analysis. Theranostics, 7(11), 2888-2899.
[14] He YH#, Chen XQ#, Yan DJ, Xiao FH, Lin R, Liao XP, Liu YW, Pu SY, Yu Q, Sun HP, Jiang JJ, Cai WW*, Kong QP*. 2016. Familial longevity study reveals a significant association of mitochondrial DNA copy number between centenarians and their offspring. Neurobiology of Aging, 47, 218-11.
[15] Xiao FH, Kong QP, Perry B, He YH*. 2016. Progress on the role of DNA methylation in aging and longevity. Briefings in Functional Genomics, 15(6), 454-459.
Book chapter:
[1] He YH, Zheng GR, Zhou DH. 2020. Senolytic Drug Development. In: Senolytics in Disease, Ageing and Longevity. Healthy Ageing and Longevity. Springer, Cham, 11, 222.
Patent:
[1] Guangrong Zheng; Daohong Zhou; Xuan Zhang; Sajid Khan; Yonghan He; Peiyi Zhang; Bcl-2 proteins degraders for cancer treatment, 2019-01-22, 3088253.
[2] Daohong Zhou; Guangrong Zheng; Yonghan He; Liya Pi; Methods of treating diseases associated with senescent cell accumulation, 2021-10-12, 507145165.