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Outbred Genome Sequencing and CRISPR/Cas9 Gene Editing in Butterflies
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| Butterflies are exceptionally diverse but their potential as an experimental system has been limited by the difficulty of deciphering heterozygous genomes and a lack of genetic manipulation technology. In order to develop butterflies as new models for exploring such topics as genetic mechanism of morphological evolution, the researchers from the Kunming Institute of Zoology (KIZ), Chinese Academy of Sciences, BGI-Shenzhen, and University of Chicago of USA construct high quality reference genomes for Papilio xuthus and P. machaon,, highly heterozygous species that differ in host plant affiliations and adult and larval color patterns. Integrating comparative genomics and analyses of gene expression yields multiple insights into butterfly evolution, including potential roles of specific genes in recent diversification. To functionally test gene fun... more |
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Adress：No.32 Jiaochang Donglu Kunming 650223 Yunnan, China Tel：86-871-5199125 |
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