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Outbred Genome Sequencing and CRISPR/Cas9 Gene Editing in Butterflies

  Butterflies are exceptionally diverse but their potential as an experimental system has been limited by the difficulty of deciphering heterozygous genomes and a lack of genetic manipulation technology. In order to develop butterflies as new models for exploring such topics as genetic mechanism of morphological evolution, the researchers from the Kunming Institute of Zoology (KIZ), Chinese Academy of Sciences, BGI-Shenzhen, and University of Chicago of USA construct high quality reference genomes for Papilio xuthus and P. machaon,, highly heterozygous species that differ in host plant affiliations and adult and larval color patterns. Integrating comparative genomics and analyses of gene expression yields multiple insights into butterfly evolution, including potential roles of specific genes in recent diversification. To functionally test gen... more
 
Seminar
Prof ZOU Quan, Tianjin University, August-14-2015
David C. Cannatella-University of Texas at Austin (...
Wang Fudi-Zhejiang University (August 12 2015)
WU Chunlian, China West Normal University (May 15 2...
DONG Guanghui, Lanzhou university (May 12 2015)
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Kunming Primate Research Center maintains AAALAC in...
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  News   more
New Partnership between KIZ and Songming Country ... (2015-04-14)
ZHENG Ping Awarded the 2015 Wang Kuancheng Award (2015-04-14)
Researchers at KIZ Win Top Honors for Third Year ... (2015-02-02)
KIZ’s Dr. Zhan-Shan Ma asks is human breast milk... (2014-11-26)
2013 Annual Yunnan Province Science and Technolog... (2014-09-29)
 

Research Progress

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Outbred Genome Sequencing and CRISPR/Cas9 Gene Editing in Butterflies

  Butterflies are exceptionally diverse but their potential as an experimental system has been limited by the difficulty of deciphering heterozygous genomes and... more
W020150519363224350999.jpg
Stability, Stability, Stability: KIZ Researchers Take a Step into a Brave New World, Identifying Filia as a Novel Regulator of DNA Damage Repair and Genomic Stability in Stem Cells

  While stem cells have either been hailed as either the holy grail of regenerative medicine or harbingers of some future techno-genetic dystopia, the reality i... more
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Smooth as Silk: Transcriptomic Study of Silkworms hints at the Genetic Basis of Silk Production

  Silkworms are both a staple of the textile industry and symbols of longstanding historical, economic and cultural significance in China, where the mulberry si... more
 
 

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