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Scientists Found Metformin Suppressed Triple-negative Breast Cancer Stem Cells
Breast cancer is the most commonly diagnosed cancer and a leading cause of cancer death in women .Breast cancer could be divided into four subtypes : Luminal A , Luminal B , HER2 , and Triple Negative Breast Cancer ( TNBC ) .TNBC , accounts for around 15% of all breast cancer cases , is an aggressive and heterogeneous disease with poor prognosis and the shortest survival rate because of no targ... more
Scientists Reveal a Novel Strategy and Effector Molecule to Protect Host Against Intracellular Pathogens
Intracellular pathogens , including bacteria , viruses and fungi , can exploit various strategies to adapt or modify the cellular environment to escape from host immune defense .However , whether the host cell has the corresponding defense strategy , the identification of the endogenous effector molecule machine and the regulatory network or not are important scientific issues have been explore... more
Collaborative Team of Scientists Determines the First High-resolution Structure of a Eukaryotic Cyclic Nucleotide-gated Channel
When we see the colorful world or smell a pleasant ( or repulsive ) scent , light or chemical signals are converted into electrical signals in our eyes and noses , signals that our brain recognizes and processes .Columbia University and Tsinghua University recently determined the first high-resolution three-dimensional structure of a eukaryotic CNG channel .This structure provides unprecedented... more
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