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First Goat Genome Sets a Good Example for Facilitating De Novo Assembly of Large Genomes
Dec. 23, 2012 — In a collaborative study published online today in Nature Biotechnology, researchers from Kunming Institute of Zoology, Chinese Academy of Sciences, BGI, and other institutes, have completed the first genome sequence of domestic goat by a robust approach integrated with next-generation sequencing (NGS) and whole-genome mapping (WGM) technologies. The goat genome is the first reference genome for s...
Five new species of loaches being discovered by Yang Jun-Xing’s research group
Watch Out！Indels may play tricks on your phylogenetic results
In evolutionary studies, insertion and deletion events (indels) are of importance. Indels refers to the mutation class that includes both insertions, deletions, and the combination, thereof, including insertion and deletion events that may be separated by many years. But, attribute to its’ enormous potential in variation,including lack of functional constraints, a high substitution rate and less homoplasy, indels...
Evidence to Track Down the Ancestor(s) of FBPase and SBPase
The genetic data benefits Scomber japonicus population development
( Scomber japonicus by CHENG Qiqun, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences) As one of the most important and familiar food fishes, Scomber japonicus (Perciformes : Scombridae) are generally predators of the open ocean, and are found worldwide in tropical and temperate waters.It is widely distributed in the coastal areas of northwestern Pacific Ocean, including China, Jap...
Shadoo Gene Differences between Cattle and Buffalo
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a class of fatal neurodegenerative maladies that affect various mammals, including cattle, sheep, mink, cervids, and human. During the past two decades, the epidemics of bovine spongiform encephalopathy (BSE) and its human form termed variant Creutzfeldt-Jakob disease (vCJD) have drawn special interests to the study of prion borne ...
Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2
Hedgehog (Hh) signaling plays pivotal roles in embryonic development and adult tissue homeostasis in species ranging from Drosophila to mammals. Malfunction of this pathway has been implicated in numerous human disorders including congenital anomalies and cancers, such as basal cell carcinoma, Medulloblastoma, lung cancer, liver cancer, etc. The Hh signaling is transduced by Smoothened (Smo), a seven-transmembrane...
Research Sheds Light on Evolutionary History of Erinaceidae
Erinaceidae is a family of small mammals that include spiny hedgehogs(Erinaceinae)，hairy moonrats and gymnures(Galericinae).Hedgehogs(erinaceines)are small,spiny nocturnal mammals that live throughout Eurasia and Africa. The closest living relatives to hedgehogs are moonrats and gymnures(galericines)which are confined to the damp forests in Southeast Asia. They are the oldest known living mammals with their evolu...
Many Algal Genes were Found Widely Distributed in Animal Genomes Through Ancient HGT
Horizontal gene transfer(HGT),the transfer of genetic material between organisms other than vertical gene transfer(transfer from the parents to offspring),is an important force in speciation and genome evolution. Almost all of these gene families are distributed in diverse animals,suggesting that they were mostly acquired by the common ancestor of animals. This work has been officially published on BMC Evolutionar...
Olfactory receptor genes, under selection or random drift?The olfactory receptor genes are in different state in dogs and wolf
Such a unique population history made it a good model to study selection and random drift,especially difference in artificial selection and natural selection. This result is a little strange,because the ecological niche has changed greatly after domestication and the olfactory receptor gene family is under strong selection,the segregating pseudogenes are important genes in the birth-and-death process for olfactory...
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