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Genetic evidence of a recent Tibetan ancestry to Sherpas in Nepal
Following the groundbreaking ascent of Mount Everest In 1953 by Tenzing Norgay and Sir Edmund Hillary, the Sherpa people gained such cachet that their name became vernacular shorthand and pop culture reference for much of the twentieth century. In Nepal today, many Sherpas rely on serve as Mountaineering enthusiasts’ Poter and guider for a living.
  Sherpas live in the Khumbu region of Nepal... more
Y-chromosome diversity suggests southern origin and Paleolithic backwave migration of Austro-Asiatic speakers from eastern Asia to the Indian subcontinent
Austro-Asiatic (AA) language has a somewhat unique geographic distribution, with a wide distribution not only in southern China and Southeast Asia, but also in India. AA is the eighth largest language family in the world in terms of population size (104 millions) with two major branches: Munda in eastern, northeastern and central India and Mon-Khmer, which stretches from northeastern India to t... more
Odyssey of Dogs
The domestic dog is the best friend of man from the animal kingdom. There are more than 400 dog breeds all over the world, each with different temperament and morphology. For this reason, they are competent to play many different roles in our livelihood. Like drug control dogs, police dogs, hunter dogs, seeing eye dogs and pet dogs.
  Although embodying so much diversity, all dogs are descend... more
Research Progress in Genetic Mechanism of High-altitude Hypoxic Adaptation in Tibetans
How to adapt to the extreme hypoxic environments at high altitude is a hot study in evolution. Tibetans are well adapted to high-altitude environments. As a complex adaptive trait, adaptation to high-altitude environment could be the result of multiple gene interactions. Previously, several candidate genes have been reported, besides EPAS1 and EGLN1 (the major upstream regulators in the hypoxic... more
Tree shrew (Tupaia belangeri chinensis) model of nonalcoholic fatty liver disease (NAFLD)
Nonalcoholic fatty liver disease (NAFLD) is defined as the presence of macrovesicalar steatosis in individuals who consume little or no alcohol. The disease spectrum of NAFLD ranges from simple steatosis to nonalcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC). The prevalence of NAFLD in developed countries ranges from 20-30%, while it is 12-24% in China.
  NAFLD i... more
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