Title: miRNA-29c suppresses lung cancer metastasis by directly targeting matrix metalloproteinase2 (MMP2) and indirectly reducing MMP9 enzyme activity

Speaker: WU Chunlian. Ph.D. (College of Life Sciences, China West Normal University)

Time: May 15 2015, Friday, 3pm

Venue: KIZ main building, conference room 234

Everyone is welcome!

Representative publications:
1. Wang HY, Wu CL, Wan SB., Zhang HJ, Zhou SW, Liu GT. Shikonin attenuates lung cancer cell adhesion to extracellular matrix and metastasis by inhibiting integrinβ1 expression and the ERK1/2 signaling pathway, Toxicology, 2013, 308:104-112.
2. WU Chunlian, Sun Jinghui, Hou Wanru. cDNA, Genomic sequence cloning and analyzing of ribosomal protein L37A gene (RPL37A) from giant panda and its over-expression. African Journal of Biotechnology, 10(77): 17700-17705, 2011.
3. Chunlian Wu, Dongru Feng, Hongling Ma, Heng Xie, HongbinWang, JinfaWang.Effect of Pinus massoniana bark extract on IFN-γ-induced ICAM-1 expression in HaCaT human keratinocytes, Journal of Ethnopharmacology, 2009,122:48-53.
4. Wang H, Zhang H, Tang L, Chen H, Wu C, Zhao M, Yang Y, Chen X, Liu G.Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis. Toxicology, 303: 139–146, 2013.
5. CHEN Yangqiong, HOU Yiling, WU Chunlian*. HOU Wanru, Cloning and sequnence analysis of ribosomal protein L23 gene from ailuropoda melanoleuca. 2012 international conference on computer science and information processing (CSIP), 510-513, 2012.
6. Wang H, Zhu Y, Zhao M, Wu C, Zhang P, Tang L, Zhang H, Chen X, Yang Y, Liu G. miRNA-29c Suppresses Lung Cancer Cell Adhesion to Extracellular Matrix and Metastasis by Targeting Integrin β1 and Matrix Metalloproteinase2 (MMP2). PLoS One. 2013, 8(8):e70192.
7. GENG Wenfeng, WU Chunlian, HOU Wanru, HOU Yiling. cDNA, Genomic sequence cloning, analyzing of ribosomal protein L36A (RPL36A) and its overexpression from giant panda. 2012 international conference on computer science and information processing (CSIP), 518-521, 2012.
8. SUN Jinghui, HOU Wanru, WU Chunlian, HOU Yiling. cDNA, Genomic sequence cloning, analyzing of ribosomal protein L19 from giant panda and its over-expression. 2012 international conference on computer science and information processing (CSIP), 514-517, 2012.

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