Title: Tipping Iron Balance in Human and Mice

Speaker: Prof Wang Fudi (School of Public Health, Zhejiang University)

Time: August 12 2015, Wednesday, 4pm

Venue: KIZ main building, third floor, conference room 327

Everyone is welcome!

Recent Publications:

1. Zhang Z, Zhang F, Guo X, An P, Tao Y, Wang F*. Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores. Hepatology. 2012; 56(3): 961-71. 

　　2. Jeong J, Walker J, Wang F, J. Park G, Palmer A, Giunta C, Rohrbach M, Steinmann B, Eide DJ. Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos Syndrome. Proc Natl Acad Sci USA. 2012; 109(51): E3530-8. 

　　3. Zhang Z, Zhang F, An P, Guo X, Shen Y, Tao Y, Wu Q, Zhang Y, Yu Y, Ning B, Nie G, Knutson MD, Anderson GJ and Wang F*. Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses. Blood. 2011; 118(7): 1912-22. 

　　4. Mu M, Wu A, An P, Du X, Wu Q, Shen X, Wang F*. Black soybean seed coat extract regulates iron metabolism by inhibiting the expression of hepcidin. British Journal of Nutrition. 2014; 111(7): 1181-9. 

　　5. Guan Y, An P, Zhang Z, Zhang F, Yu Y, Wu Q, Shi Y, Guo X, Tao Y, Wang F. Screening identifies the Chinese medicinal plant Caulis Spatholobi as an effective HAMP expression inhibitor. Journal of Nutrition, 2013; 143(7): 1061-6. 

　　6. Guo X^#, Zhou DZ^#, An P^#, Wu Q, Wang H, Wu A, Mu M, Zhang D, Zhang Z, Wang H, He L, Liu Y*, Wang F*. Associations between serum hepcidin, ferritin, hemoglobin, and type 2 diabetes risks in a Chinese Han population. British Journal of Nutrition. 2013; 110(12): 2180-5. 

　　7.Yu Y^#, Wu A^#, Zhang Z, Yan G, Zhang F, Zhang L, Shen X, Hu R, Zhang Y*, ZhangK*, Wang F*. Characterization of the GufA Subfamily Member SLC39A11/Zip11 as a Zinc Transporter. Journal of Nutritional Biochemistry. 2013; 24(10): 1697-708. 

　　8. An P, Wu Q, Wang H, Guan Y, Mu M, Liao Y, Zhou D, Song P, Wang C, Meng L, Man Q, Li L, Zhang J, Wang F*.TMPRSS6, but not TF, TFR2, or BMP2 Variants are Associated with Increased Risk of Iron Deficiency Anemia. Human Molecular Genetics. 2012; 21(9): 2124-31. 

　　9. Zhang F, Tao Y, Zhang Z, Guo X, An P, Shen Y, Wu Q, Yu Y,Wang F*. Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses. Haematologica. 2012; 97(12): 1826-35. 

　　10. Gan W, Guan Y, Wu Q, An P, Zhu J, Lu L, Jing L, Yu Y, Ruan S, Xie D, Makrides M, Gibson RA, Anderson GJ, Li H*, Lin X* and Wang F*. Association of TMPRSS6 polymorphisms with ferritin, hemoglobin and type 2 diabetes risk in a Chinese Han population. The American Journal of Clinical Nutrition. 2012; 95(3): 626-32. 

　　11. Guo L, Lichten LA, Ryu MS, Liuzzi JP, Wang F and Cousins RJ. STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells. Proc Natl Acad Sci USA. 2010; 107(7): 2818-23. 

　　12. Feng YX, Zhao JS, Li JJ, Wang T, Cheng SQ, Yuan Y, Wang F, Wang XF, Xie D. Liver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-kappaB signaling pathway. Hepatology. 2010; 51(2): 535-44. 

State Key Laboratory of Genetic Resources and Evolution