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| Estimated to afflict some 500 million people worldwide, obesity is an increasingly common problem. Numerous studies also implicate it as the number one preventable cause of death globally. Despite these realities, research into the causes and treatments of obesity are handicapped by our limited understandings into the connection between lipid metabolism—the process by which the body breaks dow... more |
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| In the long history of biomedical research, animals are always the non-replaceable parts. During the last four decades, 99% of the laureates of Noble Prize in Physiology and Medicine won the honor referring to their animal-based research. For human diseases study specifically, although the non-human primates, such as rhesus monkey, do have their undeniable advantages, the disadvantages are also... more |
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| No matter how small it is, almost every aspect of biology’s life is under the close watch of evolutionary selection. And the influence of selection could show in different ways. For example, directional selection is a mode in which the best man wins, which means a single phenotype will be favored and the allele frequency will continuously shift in one direction. But one the other hand, there a... more |
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When the Indian subcontinent collided with the Eurasian plate, many animals and plants from Africa and Madagascar dispersed into Asia. The event triggered the biotic diversification of many species — one species of particular interest is the rhacophorid tree frog.
Early studies have suggested that the India–Asia collision occurred during the Paleocene or Early Eocene, around 66–56 millio... more |
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| Despite the prevalence of colorectal cancer (CRC) around the world in general and China in particular, relatively little is known about the underlying causal mechanisms of CRC. Current research that has attempted to find novel risk factors for these disorders suggests that alongside the traditional risks of dietary, genetic, and environmental factors, bacterial infections may play a significant... more |
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