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| Co-infection with Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV) is highly prevalent in intravenous drug users (IDUs). Because of the proximity to the “Golden Triangle”, HIV prevalence among the IDUs is very high in the China-Myanmar border region. However, there are few studies about co-infection with HIV and HCV and/or HBV, especially in the region ... more |
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TheH43Y variant of TRIM5α gene might protect against HIV-1 infection in Chinese intravenous drug users, suggested LIU Fengliang, a Ph.D. candidate at Kunming Institute of Zoology, Chinese Academy of Sciences.
TRIM5α has species-specific restriction activity against HIV-1, the most common and pathogenic strain of virus. Though human also express TRIM5α protein, it is less potent in suppre... more |
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During the Last Glacial Maximum (LGM) around 20 thousand years ago, the ice sheet had extended whereas the see level had dropped. This situation had been turned over after the LGM as the climate became warmer. As a result, the eustatic movement occurred in the coastal regions of mainland and islands, and was likely to influence human dispersals in these regions.
In East Asia, the formation ... more |
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Gene duplication is one of the major sources for the origin of new genes and new functions. However, how a new duplicate gene acquires functions by integrating into a pathway and results in adaptively important phenotypes has remained largely unknown.
Recently, WANG Wen and his colleagues from Kunming Institute of Zoology,Chinese Academy of Sciences, has systematically investigated the biol... more |
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The traditional wisdom in evolutionary genetics is that essential genes are usually the older ones that have been maintained over long evolutionary time frames. Two studies of young genes in species of Drosophila reveal that in fact essential genes are just as likely to be young, and that new genes can quickly integrate themselves into key pathways to take on essential roles.
Chen and colle... more |
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