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( Scomber japonicus by CHENG Qiqun, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences)
As one of the most important and familiar food fishes, Scomber japonicus (Perciformes : Scombridae) are generally predators of the open ocean, and are found worldwide in tropical and temperate waters.It is widely distributed in the coastal areas of northwestern Pacific... more |
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As the basic units to carry heredity information of living organisms, the origins and functions of genes can be tracked back to the very beginning point of life on earth. So, when the genes which are 10 millions years old are still been considered young and new, you should not be surprised.
The new genes are not popped out in a random puff from nature. On the contrary, their débuts are the... more |
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| Protein ubiquitination regulates multiple cancer-related cellular processes, including cell cycle. Typically, it is sequentially mediated by three enzymes: ubiquitin-activating enzyme (E1), ubiquitin-conjugating enzyme (E2), and ubiquitin ligase (E3) that controls substrate specificity. During which, ubiquitin E3 ligases are considered to be the next wave of molecules for targeted therapy. Howe... more |
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| Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a class of fatal neurodegenerative maladies that affect various mammals, including cattle, sheep, mink, cervids, and human. During the past two decades, the epidemics of bovine spongiform encephalopathy (BSE) and its human form termed variant Creutzfeldt-Jakob disease (vCJD) have drawn special interests to the s... more |
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Hedgehog (Hh) signaling plays pivotal roles in embryonic development and adult tissue homeostasis in species ranging from Drosophila to mammals. Malfunction of this pathway has been implicated in numerous human disorders including congenital anomalies and cancers, such as basal cell carcinoma, Medulloblastoma, lung cancer, liver cancer, etc. The Hh signaling is transduced by Smoothened (Sm... more |
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