XU Shuhua  Ph.D.  

Education background

Dr. XU Shuhua got his Bachelor degree in 2000 and Master degree in 2003 from Hubei University, and received his Ph.D. degrees from Fudan University in 2006.

Work experience

He is Principal Investigator in CAS-MPG Partner Institute for Computational Biology. He is Max-Planck Independent Research Group Leader and Distinguished Adjunct Professorship in ShanghaiTech University.

Research field

His scientific research has focused on population genomics research of human admixture history and biological adaptation to local environment.

Award

1^st Class Prize of Natural Science Award, Ministry of Education (2018)

Chinese Academy of Sciences President's Award for Excellence (2018)

Shanghai Academic Research Leader (2016)

Distinguished Principal Investigator of Chinese Academy of Sciences (CAS) (2015)

Outstanding Member of the 1^st Chinese Academy of Sciences Youth Innovation Promotion Association (CAS) (2015)

Distinguished Young Scholars of National Science Fund (2015)

2^nd Class Prize of Natural Science Award, State Council (2015)

Expert of Pudong New Area Science and Technology Development Fund (2015)

Youth Committee Member of the 9^th Council Meeting of Chinese Society of Genetics (2013)

Outstanding Member of Chinese Academy of Sciences (CAS) Youth Innovation Promotion Association (CAS) (2013)

The National Top-notch Young Innovative Talent supported by The "Ten-Thousand-Talents" Project (“Wanren Jihua”) (2013)

Nomination Prize of the 6^th Shanghai Scientific Young Elites Program (Shanghai Government) (2012)

Thesis Advisor for 2012 SIBS-Eli Lilly Outstanding Graduate Thesis Award Winner (US) (2012)

Distinguish Young Scientist, Chinese Academy of Sciences (2012)

1^st Class Prize of Natural Science Award, Ministry of Education (2012)

Shanghai Rising-Star, bestowed by Science and Technology Commission of Shanghai Municipality (2011)

Top 100 National Excellent Doctoral Dissertation Award in China (Ministry of Education of China & Academic Degrees Committee of the State Council) (2011)

Award of the Excellent Doctoral Dissertation (Fudan University) (2010)

Chia-Si Lu Scholarship of Chinese Academy of Sciences (CAS) (2009)

Life Science Award, Shanghai, MEIJI Dairies Corp (Japan) (2009)

Sanofi Aventis (SA)-SIBS 2009 Young Faculty Award (France) (2009)

Award of the Excellent Doctoral Dissertation of Shanghai (Shanghai Municipal Education Commissions) (2009)

Project

He is the chief scientist of the NSFC project “The impact of genetic admixture at different times on genomic diversity in East Asian and South East Asian populations” and the Strategic Priority Research Program of the Chinese Academy of Sciences “Dissecting Intrinsic driving forces of evolution of animal complex traits”, etc.

His research is to understand microevolution mechanisms in human. We use computational approaches and developing new methods to dissect genetic architecture of human populations, quantitatively characterize their admixture features, and reveal their migration history and adaptive divergence.

[1]      Zhang C#, Gao Y#, Liu J, Xue Z, Lu Y, Deng L, Tian L, Feng Q, Xu S*. 2018. PGG.Population: a database for understanding the genomic diversity and genetic ancestry of human populations. Nucleic Acids Research, 46(D1), D984-D993.

[2]      Zhang C#, Lu Y#, Feng Q#, Wang X#, Lou H, Liu J, Ning Z, Yuan K, Wang Y, Zhou Y, Deng L, Liu L, Yang Y, Li S, Ma L, Zhang Z, Jin L, Su B, Kang L and Xu S*. 2017. Differentiated demographic histories and local adaptations between Sherpas and Tibetans. Genome Biology, 18, 115.

[3]      Feng Q#, Lu Y#, Ni X#, Yuan K#, Yang Y#, Yang X, Liu C, Lou H, Ning Z, Wang Y, Lu D, Zhang C, Zhou Y, Shi M, Tian L, Wang X, Zhang X, Li J, Khan A, Guan Y, Tang K*, Wang S*, Xu S*. 2017. Genetic history of Xinjiang’s Uyghurs suggests Bronze Age multiple-way contacts in Eurasia. Molecular Biology and Evolution, 34(10), 2572-2582.

[4]      Lu D, Lou H, Yuan K, Wang X, Wang Y, Zhang C, Lu Y, Yang X, Deng L, Zhou Y, Feng Q, Hu Y, Ding Q, Yang Y, Li S, Jin L, Guan Y, Su B, Kang L, and Xu S*. 2016. Ancestral Origins and Genetic History of Tibetan Highlanders. Am.J.Hum.Genet., 99, 580-594.

[5]      Lou H, Lu Y, Lu D, Fu R, Wang X, Feng Q, Wu S, Yang Y, Li S, Kang L, Guan Y, Hoh BP, Chung YJ, Jin L, Su B, Xu S*. 2015. A 3.4-kb Copy-Number Deletion near EPAS1 Is Significantly Enriched in High-Altitude Tibetans but Absent from the Denisovan Sequence. Am.J.Hum.Genet., 97(1), 54-66.

[6]      Jin W, Wang S, Wang H, Jin L, Xu S*. 2012. Exploring Population Admixture Dynamics Using Empirical and Simulated Genome-Wide Distribution of Ancestral Chromosomal Segments. Am.J.Hum.Genet., 91, 849-862.

[7]      Xu S*, Pugach I, Stoneking M, Kayser M, Jin L, The HUGO Pan-Asian SNP Consortium. 2012. Genetic Dating Indicates that the Asian-Papuan Admixture through Eastern Indonesia Corresponds to the Austronesian Expansion. Proceedings of the National Academy of Sciences, 109(12), 4574-4579.

[8]      Jin W, Xu S*, Wang H, Li Y, Shen Y, Wu B, Jin L*. 2012. Genome-Wide Detection of Natural Selection in African Americans Pre-and Post-Admixture. Genome Research, 22(3), 519-527.

[9]      Xu S*, Li S, Yang Y, Tan J, Lou H, Jin W, Yang L, Pan X, Wang J, Shen Y, Wu B, Wang H, Jin L*. 2011. A Genome-Wide Search for Signals of High Altitude Adaptation in Tibetans. Molecular Biology and Evolution, 28, 1003-1011.

[10] The HUGO Pan-Asian SNP Consortium (Jin L*, Liu ET*, Seielstad M*, Xu S*; 93 authors from 10 countries). 2009. Mapping Genetic Diversity in Asia. Science, 326,1541-1545.