1.Nahar R#, Zhai W#, Zhang T#, Takano A, Khng AJ, Lee YY, Liu X, Lim CH, Koh TPT, Aung ZW, Lim TKH, Veeravalli L, Yuan J, Teo ASM, Chan CX, Poh HM, Chua IML, Liew AA, Lau DPX, Kwang XL, Toh CK, Lim WT, Lim B, Tam WL, Tan EH, Hillmer AM*, Tan DSW*. Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing. Nat Commun. 2018 Jan 15;9(1):216. (Equal contribution)  

　　2.Zhai W？,#, Lim TK#, Zhang T#, Phang ST, Tiang Z, Guan P, Ng MH, Lim JQ, Yao F, Li Z, Ng PY, Yan J, Goh BK, Chung AY, Choo SP, Khor CC, Soon WW, Sung KW, Foo RS？, Chow PK, The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma, Nature Communications, 2017 Feb 27;8:4565 (IF 11.3, # Equal contribution) 

　　3.Chen H, Deng Q, Ng SH, Lee RT, Maurer-Stroh S, Zhai W*., Dynamic convergent evolution drives the passage adaptation across 48 years’ history of H3N2 influenza evolution Mol Biol Evol. 2016 Dec;33(12):3133-3143 (IF 13.6) 

　　4.Wang,G-D#, Zhai, W#, Yang, H-C#, Wang, L#, Zhong, L , Liu Y-H, Fan, R-X, Yin,T-T, Zhu, C-L, Poyarkov, AD, Irwin,DM, Hyt？nen,MK, Lohi, H, Wu,C-I, Savolainen,P, Zhang, Y-P, Out of southern East Asia: the natural history of domestic dogs across the world, Cell Res, 2016 Jan;26(1):21-33 (# joint first author，cover story, IF 14.8).  

　　5.Chong Z#, Zhai W#, Li C, Gao M, Gong Q, Ruan J, Li J, Jiang L, Lv X, Hungate E, Wu CI*. The Evolution of Small Insertions and Deletions in the Coding Genes of Drosophila melanogaster. Mol Biol Evol. 2013 Dec;30(12):2699-708. (# Equal contribution)  

　　6.Wang GD#, Zhai W#, Yang HC, Fan RX, Cao X, Zhong L, Wang L, Liu F, Wu H, Cheng LG, Poyarkov AD, Poyarkov NA Jr, Tang SS, Zhao WM, Gao Y, Lv XM, Irwin DM, Savolainen P, Wu CI*, Zhang YP*. The genomics of selection in dogs and the parallel evolution between dogs and humans Nat Commun. 2013;4:1860. (# Equal contribution)  

　　7.Hu Z, Fu Y-X, Greenberg AJ, Wu C-I*, Zhai W* (2013) Age-Dependent Transition from Cell-Level to Population-Level Control in Murine Intestinal Homeostasis Revealed by Coalescence Analysis. PLoS Genet 9(2): e1003326. (* co-corresponding author) 

　　8. Zhai W, Nielsen R, Goldman N, Yang Z. Looking for darwin in genomic sequences--validity and success of statistical methods. Mol Biol Evol. 2012 Oct;29(10):2889-93.  

　　9.Tao Y#, Ruan J#, Yeh SH#, Lu X#, Wang Y#, Zhai W#, Cai J#, et al Chen DS*, Chen PJ*, Wu CI*. Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12042-7. (#Equal contribution) 

　　10.He Z#, Zhai W#, Wen H#, Tang T, Wang Y, Lu X, Greenberg AJ, Hudson RR, Wu CI*, Shi S*. Two evolutionary histories in the genome of rice: the roles of domestication genes. PLoS Genet. 2011 Jun;7(6):e1002100. (# Equal contribution) 

　　11.Green RE#, Krause J#, Briggs AW#, Maricic T#, Stenzel U#, Kircher M#, Patterson N#, Li H, Zhai W, et al, Reich D*, P？？bo S*. A draft sequence of the Neandertal genome. Science. 2010 May 7;328(5979):710-22. (10 breakthroughs of the year, AAAS Newcomb-Cleveland Prize,  best paper of the year for Science, cover story) 

　　12. Zhai W, Nielsen R, Slatkin M. An investigation of the statistical power of neutrality tests based on comparative and population genetic data. Mol Biol Evol. 2009 Feb;26(2):273-83. 

　　13. Zhai W, Slatkin M, Nielsen R.Exploring variation in the d(N)/d(S) ratio among sites and lineages using mutational mappings: applications to the influenza virus. J Mol Evol. 2007 Sep;65(3):340-8. 

　　14. Zhai W, Todd MJ, Nielsen R. Is haplotype block identification useful for association mapping studies? Genet Epidemiol. 2004 Jul;27(1):80-3.