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| Two decades ago, the initial discovery of the protein prohibitin’s (PHB) function as an anti-proliferative has sparked major research initiatives geared at untangling the molecular mechanisms involved in prohibitin’s cell proliferation and tumor suppressing activities. Later research found this activity was largely controlled by the gene encoding prohibitin, leaving some question as to what t... more |
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| The Chinese tree shrew (Tupaia belangeri chinensis), a closer affinity to primates, is increasingly considered as a viable alternative animal model for biomedical research due to a variety of unique characteristics, e.g., small adult body size, short reproductive cycle and life span, low cost of maintenance. While the recently published genome of the Chinese tree shrew greatly extends the nec... more |
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| Of all human conditions, aging and death are perhaps the most universal. Unfortunately death among elderly populations is often a drawn out and painful affair, as advanced age is accompanied by marked rises in morbidity and mortality due to infectious diseases. Precisely why this is the case has been subject to a great deal of speculation, but one commonly held explanation is referred to as imm... more |
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| Labeoninae is a subfamily in the family Cyprinidae of order Cypriniformes and inhabit fast flowing freshwater. This species is characterized with their highly modified and variable lips. Labeoninae fish is high in biodiversity and the largest species richness is in the karst region around southern China. In China, there are 26 genera, of which 12 are endemic. Therefore, Labeoninae has become a ... more |
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Pore-forming toxins, such as aerolysin, are a largest group of bacterial virulent factors in pathogenic infections, which could oligomerize and form pores to the host-cell membranes, and therefore cause cellular lesions. Although it has been known that aerolysin-like proteins are also widely distribute in vertebrates, their biological functions are poorly known.
Most recently, Prof. ZHANG Y... more |
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