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MAD: Mutually Assured Defense? RNASEL and Revaluating the Biological Arms Race Between Humans, Viruses, and Cancer.
ZHANG Yaping’s lab at the Kunming Institute of Zoology (KIZ), Chinese Academy of Sciences (CAS) have been busy re-examining precisely how viruses and other organisms engage in a biological arms race with one another by studying the role of the RNASEL gene and its mutations in relation to viral infection and prostate cancer.
  The RNASEL gene plays a critical role in combating viral infection... more
AMP – the New Weapon to Fight Infection
Infection is one of the major causes of patients’ death. According to a recent survey, only in US, the annual incidence of septicemia is 750000 cases, and among them, 225000 cases will end in death. Nowadays, the antibiotics market value has rocketed to over $30 billion, but unfortunately, scientists almost had gotten nothing in developing novel applicable ones during the past half century. Ev... more
A new species of Glyptothorax fishes from Nujiang drainage of China

  Glyptothorax lanceatus-Holotype-showing living coloration, photo by Dr. Chen, Xiao-Yong from KIZ
  Glyptothorax is a most species-diverse but poorly knowing catfish genus in Sisoridae. There are about 80 valid species widely distributed throughout the entire southern arc of the Asian continent, from Asia Minor (in the Tigris and Euphrates River drainages) eastward to East Asia (in the Ya... more
The evolution of cardiolipin biosynthesis and maturation was revealed

  Fig. The evolutionary history of cardiolipin biosynthesis and maturation into three domains of life.
  Cardiolipin is an important structural and functional component of mitochondrial inner membrane in eukaryotic cells as well as bacterial membrane in prokaryotic cells. This fact has been considered to strengthen the hypothesis of the endosymbiotic origin of mitochondria. In general, how... more
Two is Better than One: MHC I A and its variants in the regulatory mechanisms of immune systems

  The latest research on Major histocompatability complex class I (MHC I) from Dr. ZHENG Yongtang’s team at the Kunming Institute of Zoology, CAS, perfectly illustrates the idea that even on a cellular level, two is better than one. Prof. ZHENG’s team examined how MHC I molecules and some of its specific variants interact to form unique structures that prolong the life of the cell and prom... more
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