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Recent study reveals the important role of Kunitz/BPTI gene family in the long-term blood feeding in hard ticks
Ticks are obligate blood-sucking ectoparasites of vertebrates throughout the world. They can transmit a wide variety of pathogens causing several human and animal diseases. Hard and soft ticks display different feeding strategies: hard ticks feed on blood for a few days to over one week, whereas soft ticks typically feed on blood for minutes to hours. Kunitz/BPTI proteins are abundant in the sa... more
A Systematic Analysis of Heart Transcriptome Highlights Divergent Cardiovascular Disease Pathways between Animal Models and Humans

  A fundamental and important parameter for developing appropriate human disease models is the knowledge of functional conservation of candidate human disease genes in the model organism. Animal models have proven useful for studying the genetic basis of cardiovascular disease (CVD), however, animal models fell short of the expected results, or even came out with opposite phenomena in many c... more
Prohibitins (PHBs) play novel role in protease activated receptor-1 mediated human platelets activation
Platelets are small disc-shaped cell fragments that undergo a rapid activation when they encounter exposed subendothelial matrix caused by vascular damage. Platelets adhere to subendothelial surfaces and become activated, causing them to aggregate and form a plug, which is responsible for primary haemostasis. Platelet activation is a complex process induced by a variety of stimuli, which act in... more
Being smart or stupid? Higher male fecundity but shorter lifespan
By reviewing the latest discovery of Kunming Institute of Zoology, the CAS, about the newly evolved gene CG11700 in drosophila,you will have to agree that “there is no free lunch” definitely is an iron rule. When the drosophila with null mutations of CG11700 have been proudly bestowed with high male fecundity, partial of their lifespan also have been deprived mercilessly.
  CG32744 and CG11... more
Listen to the song of Rana chensinensis species complex croaking on Qinghai–Tibetan Plateau
Speciation is the formation of new and distinct species, whereby a single evolutionary line splits into two or more independent ones. It is one of the key evolutionary processes and is responsible for the diversity of life that exists on Earth. For example, humans, chimpanzees and bonobos are close relatives by sharing the common ancestors and similar genetics, while, according to the analysis ... more
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