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| The Himalaya-Hengduan mountainous regions locate in southwest China, which forming the south-eastern part of the Qinghai-Tibet Plateau and adjacent from the west to the Sichuan Basin. The elevations of these regions are from 1,300 to 6,000 meters and most of the areas are covering by dense, pristine forests. Attribute to its relative isolation and the fact that most of the area remained free fr... more |
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| Breast cancer is a common malignant tumor. According to the Report of Breast Disease in China published by Chinese Population Association in 2010, the number of breast cancer patients in China was estimated to be over 200,000. Every year, about 15 percent of 1,300,000 new cases over the world were from China. High work pressure and modern diet led to a rapid increase of breast cancer patients i... more |
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| Tree shrews (Tupaia belangeri chinensis) belong to the Tupaiinae family, Scandentia order. Since tree shrew has small body size, easy to propagate and has a close relationship with primates, it is more advantageous than rodents in modeling human diseases. These features of tree shrew also make it a candidate model animal of potential human diseases and could partly substitute the high-price non... more |
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| Ticks are obligate blood-sucking ectoparasites of vertebrates throughout the world. They can transmit a wide variety of pathogens causing several human and animal diseases. Hard and soft ticks display different feeding strategies: hard ticks feed on blood for a few days to over one week, whereas soft ticks typically feed on blood for minutes to hours. Kunitz/BPTI proteins are abundant in the sa... more |
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A fundamental and important parameter for developing appropriate human disease models is the knowledge of functional conservation of candidate human disease genes in the model organism. Animal models have proven useful for studying the genetic basis of cardiovascular disease (CVD), however, animal models fell short of the expected results, or even came out with opposite phenomena in many c... more |
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