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Similar protein architectures can be used to bind identical ligands via completely different ways. Retinoids binding proteins are good case for this principle. Interestingly, although RBP, ERABP, CRBPs and CRABPs have homologous structural motifs and overlapping ligand specificity, they have different binding mechanisms.In the same family of proteins and subcellular location, the orientati... more |
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The Kunming Institute of Zoology, Chinese Academy of Sciences confirmed the existence of the world’s fifth subspecies of snub-nosed monkey “Nujiang snub-nosed monkey” in China by taking DNA analysis on their excrements collected near China’s Nu River, Yunnan province in March, 2012.
Besides the excrements, forest guards in the Gaoligong Mountains nature preserve also took pictures of a ... more |
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| Giardia, as a kind of unicellular protozoa, was once thought to be the most primitive extant eukaryote because of its many so-called primitive molecular and cellular traits and branching out very early from the eukaryote trunk on many phylogenetic trees. Thus, this creature was though to be of very important significance to studying how eukaryotes evolved from their prokaryotic ancestor. Howe... more |
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ZHANG Yaping’s lab at the Kunming Institute of Zoology (KIZ), Chinese Academy of Sciences (CAS) have been busy re-examining precisely how viruses and other organisms engage in a biological arms race with one another by studying the role of the RNASEL gene and its mutations in relation to viral infection and prostate cancer.
The RNASEL gene plays a critical role in combating viral infection... more |
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| Infection is one of the major causes of patients’ death. According to a recent survey, only in US, the annual incidence of septicemia is 750000 cases, and among them, 225000 cases will end in death. Nowadays, the antibiotics market value has rocketed to over $30 billion, but unfortunately, scientists almost had gotten nothing in developing novel applicable ones during the past half century. Ev... more |
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