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Adaptation to extreme environmental conditions is one of the major topics of evolutionary biology. High elevations provide extreme environments challenging the survival of many species. It is of strategic and scientific significance to study the mechanism of Plateau adaptation, especially given that China has the largest plateau areas in the world.
In particular, the Qinghai-Tibetan Plateau... more |
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| Triplophysa is an ecologically important and taxonomically challenging genus distributed in lakes, rivers, and streams of the Qinghai-Tibetan Plateau and adjacent regions. Species of Triplophysa are distributed westward to the Aral Sea basin and across interior drainages of Baluchistan and northwestward to Western Mongolia and adjoining Russia. Recently, scientists found four new member of Trip... more |
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Tissue repair is a common problem during animal survival; however, scar tissue formation is a common by-product of human wound healing, which can lead to severe clinical dysfunction. Therefore, how to promote tissue regeneration and repair while reducing scar formation is an important issue.
Amphibian skin plays an important physiological role in breathing and hydro-salinity balance, and it... more |
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Heterogeneity is a basic characteristic of cancer, including intra-tumor heterogeneity and heterogeneity among patients mainly due to a variety of genetic alterations. The latter may give rise to differences in the responses to therapies.
Glioblastoma (GBM) is the most common and malignant tumor of the brain parenchyma. The median survival of GBM patients is only 12–15 months, althoug... more |
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New frontiers in the allele-specific RNA editing research
The regulation of biallelic gene expression is important for development in diploid organisms and is associated with several human diseases. A large class of genes has been demonstrated to be highly expressed in only one allele including random monoallelic expression, parental-specific (imprinted) expression, and sequence allele-spec... more |
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