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Heterogeneity is a basic characteristic of cancer, including intra-tumor heterogeneity and heterogeneity among patients mainly due to a variety of genetic alterations. The latter may give rise to differences in the responses to therapies.
Glioblastoma (GBM) is the most common and malignant tumor of the brain parenchyma. The median survival of GBM patients is only 12–15 months, althoug... more |
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New frontiers in the allele-specific RNA editing research
The regulation of biallelic gene expression is important for development in diploid organisms and is associated with several human diseases. A large class of genes has been demonstrated to be highly expressed in only one allele including random monoallelic expression, parental-specific (imprinted) expression, and sequence allele-spec... more |
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| Spicy foods elicit a pungent or hot and painful sensation that repels almost all mammals. Prof. LAI Ren’ group from Kunming Institute of Zoology, Chinese Academy of Sciences and researchers from Zhejiang University observed that tree shrews (Tupaia belangeri chinensis), which possess a close relationship with primates, can directly and actively consume chili peppers, despite the deep geographi... more |
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| The central nervous system is the most complicatedly and precisely regulated organ in vertebrate. It is also critical for both primary nervous activity, such as sense perception, emotion regulation and body maintenance, and higher nervous activity, such as thinking, cognition and consciousness. One of the most important traits of brain is the storage of massive information, i.e. the ability and... more |
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| Identified in the 1940s in Africa, Zika is primarily spread by the bite of an infected mosquito. It can be passed from a pregnant woman to her fetus, leading to defects in infants, including microcephaly that causes abnormally small brains and heads. Since 2015, the Zika virus (ZIKV) has swept through more than 60 countries. The epidemic led the World Health Organization to issue an alert in De... more |
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