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In 1838, “Roof of the World” was first used to describe the Pamirs by the British explorer John Wood. The high altitude makes the Pamirs a big challenge in human dispersal in Central Asia.
The terrible traffic and environment made the investigation of population genetics difficult in this region. Therefore, the settlement history is still unclear in the Pamirs.
To address this issue, ... more |
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| Recently, by using a systematic integrative analysis based on the largest collection of brain expression profiles of Alzheimer’s disease (AD) and other AD related omics data, researchers identified several upstream regulator genes which may play a crucial role in regulatory network of gene expression in AD brain. The study suggested that targeting the expression of these upstream regulators in... more |
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China has the highest diversity of cave fishes in the world. There are more than 100 species recorded in China. According to the necessity of cave environment, cave fishes are divided into 3 types: typical cave fishes, atypical cave fishes and accidental cave dwelling fishes.
Triplophysa is the largest groups in the family Nemacheilidae (Cypriniformes), most of which are so far known from C... more |
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The laboratory rat, which has been widely used in biomedical research as an animal model for ~160 years, is commonly believed to be domesticated from wild brown rat. Compared to their wild ancestors, laboratory rats exhibit different morphological, physiological and behavioral attributes. However, the genetic mechanisms underlying these phenotypic differences remain elusive.
Researchers inc... more |
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Over the years, human have imposed strong artificial selective pressure on chicken through breeding, leading to chicken varieties displaying a myriad of phenotypes.
With regard to body size, the broiler or game fowl (>5Kg) could be 10 times heavier than ornamental chickens (<500g). Being an important economic trait, body size is a hot topic among breeders and scholars alike. Dwarfism trait ... more |
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