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The laboratory rat, which has been widely used in biomedical research as an animal model for ~160 years, is commonly believed to be domesticated from wild brown rat. Compared to their wild ancestors, laboratory rats exhibit different morphological, physiological and behavioral attributes. However, the genetic mechanisms underlying these phenotypic differences remain elusive.
Researchers inc... more |
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Over the years, human have imposed strong artificial selective pressure on chicken through breeding, leading to chicken varieties displaying a myriad of phenotypes.
With regard to body size, the broiler or game fowl (>5Kg) could be 10 times heavier than ornamental chickens (<500g). Being an important economic trait, body size is a hot topic among breeders and scholars alike. Dwarfism trait ... more |
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According to the online data from American Museum of Natural History (http://research.amnh.org/herpetology/amphibia/index.html) (dated at 2017-5-30), there are in total of 41 species of the genus Fejervarya (family Dicroglossidae). Among them, eight species can be found in Thailand.
Recently, from the specimens collected from Ban Tha Khanun, Thong Pha Phum District, Kanchanaburi Province, T... more |
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Breast cancer is a common female malignant tumor. The triple negative breast cancer (TNBC), a type of breast cancer, lacks effective therapeutic targets. Patients are prone to recurrence and metastasis. Therefore, it is urgent to identify new therapeutic targets and develop effective drugs to improve the survival rate of patients with TNBC.
The previous studies have shown that transcription... more |
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| Recently, a research group led by Dr. YAO Yonggang and Dr. XU Lin at Kunming Institute of Zoology (KIZ) of Chinese Academy of Sciences in collaboration with Dr. DING Yuqiang at the Tongji University, found that Atg5- and Atg7-dependent autophagy in dopaminergic neurons regulates cellular and behavioral responses to morphine (Fig. 1). This research is published online in Autophagy: http://www.ta... more |
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