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CAS Scientists Propose New Concept for Defining and Measuring Individual-level Genetic Diversity

  Summary: A team led by CAS Fellow Ya-Ping Zhang and Prof. Zhanshan (Sam) Ma (Chinese Academy of Sciences) recently proposes a new concept, termed “individual-level genetic diversity.” The new concept is contrastingly different from existing concepts of genetic diversity, since existing genetic diversities (heterogeneities) have been traditionally defined and measured for population(s), r... more
Anna Karenina principle and human microbiome-associated diseases

  Summary: In a paper published recently in Cell Press’s iScience, Professor Zhanshan (Sam) Ma (Chinese Academy of Sciences) tested the applicability of AKP (Anna Karenina principle) to the human microbiome-associated diseases, and further discovered that AKP effects are primarily influenced by highly dominant microbial species and less influenced by rare species.
  The AKP refers to obse... more
Jejunal Resection and Anastomosis—an Applicable Method in Non-Human Primate AIDS Study

  AIDS (acquired immunodeficiency syndrome) is a transmissible disease of the immune system caused by the human immunodeficiency virus (HIV). HIV weakens a person’s immune system by destroying important cells that fight disease and infection.
  The intestinal mucosa is among the earliest and most serious targets of HIV infection. However, due to technical and other difficulties, studies o... more
Scientists Discovered New Species of the Genus Leptobrachella (Anura: Megophryidae) from Yunnan, China

  Yunnan province is the most Southwest province of China. By neighboring Vietnam, Laos and Burma, it has a 4, 060 km long borderline. Yunnan province is a land of various ethnic groups, landscapes, natural scenery, creatures, etc.. The south area of Yunnan province belongs to the Indo-Burma biodiversity hotspot, which are featured with the extremely rich animal and plant resources.
  Duri... more
Researchers Found New Mechanisms that PAQR4 Regulated Chemoresistance in Non-Small Cell Lung Cancer through Inhibiting Nrf2 Protein Ubiquitination and Degradation
  Lung cancer is the predominant cause of cancer related deaths. Within the main types of lung cancers, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), NSCLC accounts for approximately 85%, with a poor 5-year survival of only ~15%. Despite the significant progress in treatment options, prognosis remains poor because of the locally advanced metastatic tumors in most patie... more
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