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Stability, Stability, Stability: KIZ Researchers Take a Step into a Brave New World, Identifying Filia as a Novel Regulator of DNA Damage Repair and Genomic Stability in Stem Cells
While stem cells have either been hailed as either the holy grail of regenerative medicine or harbingers of some future techno-genetic dystopia, the reality is that using stem cells is fraught with numerous practical and theoretical obstacles. Current studies into the use of stem cells strongly suggest that stem-cell based therapies have immense clinical potential, from growing tissues or organ... more
DNA methylation increases the lifespan of humans
Longevity is a topic arouses extensive discussions. From ancient monarch to modern scientists, people are enthusiastic in trying to find the secrets behind longevity. So far, a well accepted notion is that human longevity is a rather complicated phenomenon involving both genetic and environmental factors, i.e., family history, genetic background, personal living and dieting habits, exercise rou... more
China’s Next Top Model: KIZ Launches the New “Tree Shrew Database”
As part of the Kunming Institute of Zoology, Chinese Academy of Science’s (KIZ, CAS) goal of developing novel animal models of human diseases, research groups at the institute have spent a great deal of time studying the Chinese tree shrew. Usng tree shrews models in place of traditional primate models has become increasingly popular, largely due to the tree shrew’s cheaper cost, smaller siz... more
Ya-Ping Zhang’s research group develops online database for dog and wolf genomes
An old adage holds that friends should share, so it is of little surprise that man’s best friend—domesticated dogs—share many of the same diseases as humans. Recent studies in dog genomics have helped scientists explore many of the genetic mechanisms underlying shared diseases between canines and humans, including cancer and neurological disorders.
  A great deal of genomic research has fo... more
Research progress of phylogeography on scimitar babbler in Yang’s Lab
Species-level paraphyly inferred from mitochondrial gene trees is a prevalent phenomenon in phylogenetics and phylogeography, but there are several potential causes (e.g. deep coalescence, introgression) representing various evolutionary processes. Previous molecular systematics on P. ruficollis also suggested plausible mitochondrial-gene-tree paraphyly of Pomatorhinus ruficollis (on Asian main... more
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