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β-catenin is a protein that helps regulate gene transcription and binding cells to create larger structures. As such, β-catenin is important to normal embryonic development and is linked to tumor development and cancer. Therefore, targeting β-catenin as a way to treat cancer has received a lot of scientific attention, but the factors involved remain unclear.
Mao’s research team has isol... more |
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| Mitochondrial DNA (mtDNA) marked widely used in evolutionary studies, especially in studies on human evolutionary history. At present, a large number of mtDNA genome sequences have submitted to public databases, but the quality of the data is not always perfect. Recent studies on the quality of human mtDNA found that sample contamination and sequencing errors exist, and such errors are not infr... more |
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| The Human Genome Project, the biggest biomedical project humans have ever endeavored to the date, greatly accelerated the advancement of DNA sequencing technologies. Three generations of DNA sequencing technologies have been developed in the last three decades, and we are at the crossroads of the second and third generations. The upgrade to the third-generation single molecule sequencing techno... more |
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Novel genes are so called because their functions differ from their parental genes. While several theories have been explored to explain the diversification of gene functions, including duplication and retrotransposition, the origin of novel genes remains a longstanding debate in evolutionary biology, and understanding this process can help scientists to better understand how humans evolved.
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| High-altitude hypoxic environments are an extreme test of survival for humans and mammals alike. The Qinghai Tibetan Plateau is one such environment. Dogs have followed humans in their settlement patterns since ancient times, even to the wilds of the Tibetan plateau, and share similar adaptive abilities with humans to living at such extreme altitudes, by while the adaptive abilities of humans h... more |
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