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| As part of the Kunming Institute of Zoology, Chinese Academy of Science’s (KIZ, CAS) goal of developing novel animal models of human diseases, research groups at the institute have spent a great deal of time studying the Chinese tree shrew. Usng tree shrews models in place of traditional primate models has become increasingly popular, largely due to the tree shrew’s cheaper cost, smaller siz... more |
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An old adage holds that friends should share, so it is of little surprise that man’s best friend—domesticated dogs—share many of the same diseases as humans. Recent studies in dog genomics have helped scientists explore many of the genetic mechanisms underlying shared diseases between canines and humans, including cancer and neurological disorders.
A great deal of genomic research has fo... more |
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| Species-level paraphyly inferred from mitochondrial gene trees is a prevalent phenomenon in phylogenetics and phylogeography, but there are several potential causes (e.g. deep coalescence, introgression) representing various evolutionary processes. Previous molecular systematics on P. ruficollis also suggested plausible mitochondrial-gene-tree paraphyly of Pomatorhinus ruficollis (on Asian main... more |
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β-catenin is a protein that helps regulate gene transcription and binding cells to create larger structures. As such, β-catenin is important to normal embryonic development and is linked to tumor development and cancer. Therefore, targeting β-catenin as a way to treat cancer has received a lot of scientific attention, but the factors involved remain unclear.
Mao’s research team has isol... more |
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| Mitochondrial DNA (mtDNA) marked widely used in evolutionary studies, especially in studies on human evolutionary history. At present, a large number of mtDNA genome sequences have submitted to public databases, but the quality of the data is not always perfect. Recent studies on the quality of human mtDNA found that sample contamination and sequencing errors exist, and such errors are not infr... more |
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