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The reason of Yunnan Province being an area with high frequency of HIV is complicated. One of the possible explanations is the special geographic location of Yunnan with miles of shared borders with several south-eastern Asia countries which lets HIV easily spread across borders. Recently, the research group headed by Prof. ZHENG Yongtang from Kunming Institute of Zoology (KIZ) of Chinese A... more |
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The human immunodeficiency virus (HIV) is the acquired immunodeficiency syndrome (AIDS) caused by a lentivirus. The treatment of HIV/AIDS usually includes the use of multiple antiretroviral drugs to act on different viral targets, which is also known as highly active antiretroviral therapy (HAART). Nucleoside reverse transcriptase inhibitors (NRTIs), as the essential components in HAART, are ab... more |
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Herbal medicine, as an important form of the Chinese traditional medicine, has a history of more that 2000 years. However, although people have been depending on them to relieve symptoms and cure diseases, the underlying biomedical mechanisms are quite little to known. For example, the Tongshu Capsule (TSC), which is composed by eight traditional Chinese medicines: notoginseng, scandent sch... more |
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As a type of breast cancer with poorest prognosis and high relapse rate, the triple-negative breast cancer (TNBC) is characterized with no expressions of the genes of estrogen receptor (ER), progesterone receptor (PR) and Her2/neu. And because most chemotherapy need to target at one of the three receptors, the lack of gene expressions in TNBC has made it difficult to treat and often require com... more |
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During the history of novel drug research and development, significant differences between mice, rats, dogs, monkeys and humans in drug absorption, distribution and excretion have resulted in massive losses and even total failures of drug application. Therefore, the availability of appropriate animals is critical for drug discovery. In recent years, tree shrews (Tupaia belangeri chinensis) ... more |
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